天津真人百家乐生物科技有限公司
天津真人百家乐生物科技有限公司


多年開發積累的核心生產工藝專長

Suzuki, Heck and Sonogashire Couplings
Chiral Heterocyclic Transformations
Protections of Amino Acids and their Derivatives (Fmoc-, Boc-) 
Liquid Phase Peptide Synthesis
Freidel-Crafts Acylation and Alkylation 
Thiophosgenation and Phosgenation
Fluorination, Bromination and Iodination
Acetoacetylation and Acrylation 
Amidation and Amination 
Azidation, Carbonylation and Carboxylation 
Cyanomethylation and Cyclization 
Diketene and Ketene Reactions
Epichlorohydrin Chemistry and Epoxidation
Hydrazine Chemistry and Reactions
Hydroformylation and Hydrosilylation
Nitromethylation and Nitrosation 
Olefin Metathesis
Optically Active Cyanohydrin 
Para- and Ortho-Methylation
Peroxidation and Silylations
Sulfochlorination, Sulfonation and Sulfoxidation 
Thiocarbonylation and Tosylation 
Transamination and Transesterification

 

有著豐富經驗並且擁有創新精神的研發團隊:
61個項目人員,其中博士6位, 碩士16位以及49位學士 (不包括定製生產部分)

先進的基礎設施和儀器設備:
7000 FT2實驗區, 35 間實驗室
配備多台分析檢測設備:2 Bruker NMRs, Shimadzu LC/MS, 和 Shimadzu HPLCs等
生產實力:
生產基地設有QA,多功能實驗室、高壓車間、生產車間等。多功能實驗室擁有100ml至50L玻璃反應器,可提供克級至公斤級的產品;高壓車間擁有從1L至500L不鏽鋼高壓反應釜;生產車間配備了搪玻璃、不鏽鋼、襯TEFLON三種材質的反應釜,容積從100L至3000L,總容量為52720L,滿足了各種定製化學品的開發和各種不同類型反應的需要,為客戶提供克至噸位級產品,溫度從-78℃至300℃,壓力高達0.16Mpa。
公司在以下的單元反應中擁有豐富的操作經驗: 硝化/還原/重氮化/加氫/鹵代/格氏/氟化/氰化/傅克/水解/脫鹵素/脫氨基/烷基化/酰化/酯化/烷氧基化/氧化反應等。
部分的核心化學技術平台:

Aldo condensation Baeyer -Villiger oxidation
Birch reduction    Claisen condensation
Curtius       Dieckmann cyclization 
Diels-Alder             Doebner-Knoevenagel condensation
Freidel-Crafts acylation   Freidel-Crafts reaction
Fries rearrangement   Gabriel synthesis
Gomberg-Bachmann reaction  Grignard reaction 
Heck reactions      Hoesch, Japp-Klingemann Perking 
Hoffman degradation     Hofmann’s reaction
Mannich reaction        Michael addition
Mitsunubo reaction Reformatsky reaction
Ritter reaction     Rosenmund reduction
Sandmeyer reaction       Schiff base reduction
Schotten-Baumann reaction   Skraup synthesis
Strecker amino acid synthesis  Sugasawa reaction
Suzuki & Sonogashire coupling   Suzuki reaction
Suzuki/Heck coupling         Swern oxidation
Ullman reaction    Vilsmeier-Haack reactions
Wilgerodt reaction     Williamson synthesis
Wittig reaction